• Ellen DeGeneres as Ellen Richmond
• Jim Gaffigan as Rusty Carnouk
• Emily Rutherfurd as Catherine Richmond
• Martin Mull as Ed Munn
• Kerri Kenney as Pam
• Cloris Leachman as Dot Richmond
• Diane Delano as Bunny Hoppstetter

Guest stars

• Regan Burns as Officer "B" Arthur (Walden Pond) (Joe)
• John Francis Daley as Erik (Walden Pond)
• Susan Yeagley as Waitress (Chain Reaction)
• Marissa Jaret Winokur as Tina (Vanity Hair)
• Tom Poston as Joe (Joe)
• Betty White as Mrs. Gibson (Missing the Bus)
• Dakota Fanning as Young Ellen (Missing the Bus)
• Mary Tyler Moore as Aunt Mary (Ellen's First Christmess)
• Maureen McCormick as Rita Carter (Shallow Gal)
• Kaley Cuoco as Vanessa Carter (Shallow Gal)
• John Ritter as Percy Moss (Gathering Moss)

Text from Wikipedia (Creative Commons Attribution-ShareAlike License).